More than 100 years ago, scientists at what is now Case Western Reserve University in Cleveland, Ohio gave the nation pride in the beginnings of medical imaging. The X-ray discoveries in 1895 by Roentgen in Germany were in the same year replicated in CWRU’s physics department by Professor Dayton Miller and thus began a long and rich history of imaging physics at the university. Ohio’s industry also had a pioneering start in the manufacturing of imaging equipment more than 80 years ago, when Picker X-Ray moved to Cleveland. Picker and other Ohio companies expanded their product development to magnetic resonance imaging (MRI), another medical revolution with CWRU roots. Last but not least, Paul Lauterbur earned an undergraduate degree at CWRU and shared the 2003 Nobel Prize in Medicine for his independent discovery of MRI.